Sport obermeyer, Ltd. Case Study Example | Topics and Well Written Essays - 750 words

Sport obermeyer, Ltd. - Case Study Example Employing use of 1,200 units would also assist in faster production and achievement of the 10 percent capacity target before the end of projected seven months. Choice of 1,200 units remains consistent and convenient for other styles used by Obermeyer. Forecasts of all the individuals in Exhibit 10 range up to 20, 000 units, therefore, affirming consistency with Wally’s production projection. The units would also not face more stringent rules because Hong Kong places fewer restrictions on minimum orders quantities for a given company. Therefore, the company would experience fewer risks in sourcing the units. It is imperative that quality products result from the use of manageable units. Obermeyer should conduct time operational change in the process of sourcing and production of raw materials. Conducting time operational change would involve reducing the period of acquiring raw materials from suppliers. Initially, Obersports suppliers took a longer time of 90 days to supply raw materials that consequently slowed the production process. Time operational change would ensure prompt production and improvement in performance of the company. Consequently, reducing period of sourcing raw materials and production process would effectively help Obersports to meet its market demands. Obermeyer should conduct market research and establish stronger business links with its retailers. Apparently, sale of Obermeyer products remains seasonal with its peak on December and January. Operational change that would ensure timely delivery of products in large quantities to trusted retailers would improve sales. Obermeyer should give its established retailers goods on credit to ensure timely delivery to the market. Obermeyer should conduct publicity campaigns to accelerate the popularity of its produce among retailers and customers. Proper advertisement would solve issues associated with retail replenishment orders. Currently, selling of Obersports products fluctuates throughout the

OXIDATION OF METHIONINE BY SINGLET OXYGEN Essay

OXIDATION OF METHIONINE BY SINGLET OXYGEN - Essay Example Its electron arrangement is different from abundant normal diradical triplet oxygen. Singlet oxygen can be formed from triplet oxygen with the assist of photosensitizers, like Rose Bengal. Such compounds use light to convert triplet into singlet oxygen. Due to low activation energy and its electron configuration singlet oxygen is a highly reactive molecule and can readily form bonds with a number of organic molecules. It is less stable than the normal form of oxygen. However, depending on the environment singlet oxygen has the possibility to exist for more than one hour at room temperature. (Schweitzer, et al., 2003) One of the reactions that singlet oxygen can take part in, is the oxidation of amino acid residues of proteins. Cysteine and methionine residues are particularly susceptible to such forms of oxidation. In contrast to oxidation of other amino acids, this type of oxidation is reversible. Both R- and S-stereoisomers of methionine sulfoxide form as a consequence of methionin e residue oxidation. The reaction can be reversed with the aid of stereospecific methionine sulfoxide reductases which can be found in most cells. The enzyme catalyses the formation of methionine residues from methionine sulfoxide (Carey, et al., 1984). ... (Stadtman, et al., 2005) This work, for example, uses methionine oxidation by singlet oxygen, generated using Rose Bengal and laser as a radiation source. This report is initially focused on describing the key literature associated with oxidation of methionine by singlet oxygen, highlighting relevant for the project issues and arguments, then moving on to presenting the research that has been done so far, making accent on the methods used and results achieved, before finally identifying the existing gaps in the study and setting up a plan for future work. Singlet and triplet oxygen Triplet oxygen is the most stable and abundant form of oxygen. The difference between two forms of oxygen can be seen by comparing the molecular orbitals of both forms (Figure 1). Figure 1: Triplet (left) and singlet (right) form of oxygen. (Min and Lee, 1999) (Frimer, et al., 1985) To define spin states of molecules spin multiplicity is used. It can be described as 2S+1. Here S is the spin quantum number, which is 1 for triplet oxygen. Therefore, the spin multiplicity for triplet oxygen is 3 and it is paramagnetic. Triplet oxygen easily reacts with radicals, but peptides in general and methionine in particular are in the singlet state. Singlet oxygen, in contrast, has different electron configuration in the ?-antibonding orbital. It is a non-radical, electrophilic molecule. The spin quantum number is 0 and multiplicity is 1, these parameters characterise the form of oxygen presented on the Figure 1 as a singlet. It does not follow the Hund’s rule, extremely reactive and 22.5 Kcal/mole higher in energy then triplet oxygen. Five excited states are produced due to electron repulsion. The 1? represents the singlet form which is responsible for the reaction with